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[Stem and Progenitor Cells | Biological Scaffolds]

CD31+/ CD45- ECFCs™
Endothelial Colony Forming Cells

CD31, a single-pass type I transmembrane glycoprotein, is typically expressed on endothelial cells, platelets, leukocytes, and their precursors. On a cell, CD31 mediates adhesion between cells that express CD31, namely endothelial cell-endothelial cell adhesion and leukocyte-endothelial cell adhesion. At this time, there is no enzymatic activity known to be associated with CD31.

Endothelial Colony Forming Cells (ECFCs) have not only the molecular but also functional characteristics of endothelial cells
in vitro and in vivo. They are negative for CD45, a tyrosine phosphatase receptor found in high concentration on various leukocyte lineages, further suggesting  hat these are the true endothelial progenitor cells.

Areas of research interest for ECFCs include tumor blood vessel development, blood vessel growth and repair, tissue ischemia, vasculogenesis and angiogenesis.


ECFCs™ differentiating to form tube-like capillaries when stimulated in vitro.

 

Ordering Information

ECFCs from Cord Blood
Catalog Number
Aliquot
26-5001-19
500,000 Cells
26-5001-21
1,000,000 Cells
26-5001-23
5,000,000 Cells

        Download Technical Bulletin Number 2

       Download a Reference List for ECFCs

         Download the Quality Specifications

       Request More Information

ECFCs are sold under license from EndGenitor Technologies, Inc.

Endothelial Colony-Forming Cells and ECFCs are trademarks of EndGenitor Technologies, Inc.

ECFCs are covered under US patent 20050266556 and foreign counterparts.

CD refers to Cluster of Differentiation.

Copyright 2008, Dynacell Life Sciences, LLC.

THESE PRODUCTS ARE FOR RESEARCH USE ONLY. Not approved for human or veterinary use, for application to humans or animals, or for in vitro diagnostic or clinical procedures.
WARNING: Preserved Cells CONTAIN HUMAN SOURCE MATERIAL, TREAT AS POTENTIALLY INFECTIOUS.